BitLocker is easy to setup, it will automatically enable the TPM chip for you and prompt to save/print the recovery key. The biggest advantage I have seen is performance when compared with other whole disk encryption technologies. In my own studies, comparing BitLocker with another well known competitor, BitLocker encrypted drives have seen almost zero performance impact. Drives encrypted with the competition literally dropped in read/write performance by 50%.
BitLocker is used in my environment for laptop drives and it meets our Coporate security compliance needs. If you try to reboot to safe mode or swap the hard drives, the laptop will prompt for the key to be entered before booting to Windows.