In our organization, the manual testing guys write manual test cases through Excel. Then they import them to ALM. They'll move in all the details. Based on that, the automation team will take care of developing the scripts through Micro Focus Unified Functional Testing and they'll add the script into the test plan.
Once the lead has approved the test plan he will move all the test cases into the test labs. If any defect is found in new releases, it is logged in the defects column.