Our primary use case with Veeam Backup & Replication is to backup critical data. We would recommend that a person put on a Veeam backup service so that in a disaster recovery scenario you set what has to come back up first because that is going to be the critical information that has to go back up as quickly as possible. You can put anything on critical servers, but we recommend that you use it for critical data that it is going to be restored within a four hour timeframe.
Veeam Backup & Replication can be deployed as agent-based or you can set it up to replicate back to a NAS, some sort of device onsite, so that a copy of your data goes to the device onsite and another copy goes to a data center for a backup as well. Then, if that server crashes, the device that's at the location has the latest copy of the good data from where they get the backup.