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How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?


What are the pros and cons of each?

ITCS user
11 Answer

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Top 5Real User

cisco hyperflex hs series vs nutanix acropolis aos

Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multicloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis.

We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrated Managed Controller was a nice feature to have. It is expandable, stable, and has good redundancy. If you require more processor cores per box, Cisco HyperFlex is a good solution for you. Support will depend on the type of contract you have, with some requests taken care of immediately and others taking longer according to the engineer’s expertise.

While Hyperflex is designed for any company size, I wouldn’t recommend them for small businesses. It also requires a solid knowledge of Cisco products, as the UI can be difficult to manage. Upgrading to a newer version can also be cumbersome and could use some improvement.

We chose Nutanix because it is easier to use and is more cost-effective. Nutanix allows us to deploy, run and scale applications both on-premises and in the cloud. It has excellent support. You can log the query straight to a technical expert, which is good if you have staff not familiar with AOS. It is easy to scale by adding new nodes, and the company is constantly adding new features.

Nutanix is not for everyone, though. The Nutanix Cloud System can be complex to maneuver when at the command line or when troubleshooting.


Nutanix is better for medium-sized companies and when you need a cost-effective solution. Cisco Hyperflex is a complete solution but is better suited for large enterprises. It works better if you are already a Cisco user.

Find out what your peers are saying about Cisco HyperFlex HX-Series vs. Nutanix Acropolis AOS and other solutions. Updated: September 2021.
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