Not so far, but we've only started using it on 4 of around 110 servers so far. We have our hands full trying to shake out many issues in order to keep it running in production mode so far. Revised: Now operational on 121 instances of SQL Server and no problems have been observed with scalability.

We do have trouble with scalability. We backup a large number of databases across our enterprise. It has a hard time handling the influx of backups when they happen all at once. We are backing up on average somewhere in the neighborhood of about 50,000 to 70,000 backups running during the course of the day. Sometimes, it has a hard time keeping up with this.