I am an end-user at an organization that uses CrashPlan PROe, and I can attest that my MacBook Air boots up quickly, with no lag or delay.
I've also met with some of the folks at Code42, and find them all to be very helpful, friendly, and knowledgeable. I recommend them frequently. Give them a call, if you're checking out backup/recovery solutions.
I just love the security/safety of having my Mac backup automatically, without me having to think about or do anything to ensure my data is secure and recoverable. I travel frequently, and I can be pretty rough on equipment, moving from place to place in a hurry (don't tell my IT guys), so having backups that I don't have to think about is just great.