What is the biggest difference between Cisco HyperFlex and VxRail?

VxRail integration with VMware is the key differentiator. VxRail comes with vSAN, management through vCenter, All flash and hybrid nodes, recover point for VM, and vSphere replication. It also has a feature of Smart fabric services, supported with Dell switches, VCF supports with SDDC and VxRail manager as core components. One click full stack automated and patch deployment is the wornderul feature which again differnciate it from all other HCI vendors.

One biggest change is the Future Proof Loyalty Program from VxRail with the following terms:
- 3-year Satisfaction Guarantee
- Hardware Investment Protection
- Predictable Support Prices
- All-Inclusive Software
- Never-Worry Data Migrations
- Cloud-enabled

This is for free, and no other competitors are providing the same.

This below URL contains more details about the program offering:
https://www.dellemc.com/en-us/products/future-proof-program.htm

- HyperFlex has encryption over expensive SED disks, however, VxRail has it enabled over the normal disks.
- HyperFlex has virtual storage appliance which is a VM managing the storage access, however, VxRail is based on built-in vSAN technology where no VMs or appliances are required to manage the storage.