I use this on a few of my servers. This does a great job with scheduling full backups and incremental backups. Support is good due to it being an enterprise product.
Room for Improvement:
Sometimes permissions and deploying the agents can be tricky. I found that running as a local admin works better than domain admin. Some tape drives it has issues with, and doesn't like certain tape manufacturers.
I have mostly moved away from this to Amanda backup, due to it being open source (free!!). A few years ago, this would be all that I trust to do backups, but now it is no longer needed.
Disclosure: I am a real user, and this review is based on my own experience and opinions.
Jul 23 2012